Entering the 2025 season ranked No. 2 and expected to contend for a national title, the Penn State Nittany Lions instead slipped to a 3–4 overall record, 0-4 in Big Ten play, and watched their playoff hopes evaporate in real time.

The Nittany Lions quarterback grew up near Columbus among Buckeyes fans. He has dreamed of playing at Ohio Stadium.

The latest betting number is Ohio State -20.5, per the DraftKings website. Three touchdowns. Penn State is missing key starters Drew Allar and Tony Rojas, who are out with long-term injuries. Ohio State is 10-1 in its last 11 meetings with the Lions. Penn State’s last victory over the Buckeyes occurred in 2016 at Beaver Stadium.

Penn State's still looking for its first Big Ten win. Here's seven players looking to spoil Ohio State's impressive 2025 season.

FIRST AND TEN The No. 1/1 Ohio State Buckeyes (7-0; 4-0 Big Ten) host the Penn State Nittany Lions (3-4, 0-4) in a 12 noon game at Ohio Stadium that FOX

This year’s edition of the Penn State-Ohio State contest has lost a lot of luster in recent weeks due to the Lions starting Big Ten play 0-4. What was once thought to be one of the best games of the season and a likely play-in game for the College Football Playoff has turned into PSU

Ohio State will pay tribute to two late players, Nick Mangold and Bob Maggs, before the Buckeyes kick off against Penn State on Nov. 1.

Since a narrow Week 4 loss to Oregon, the Nittany Lions have dropped four straight, including defeats to UCLA, Northwestern, and Iowa, each one sealed by a late defensive breakdown. With quarterback Drew Allar out for the season, Penn State’s offense has sputtered, ranking 100th nationally in total yards.