Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...
Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or ...
As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...
Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to ...
Neurons are important, but they are not everything. Indeed, it is "cartilage," in the form of clusters of extracellular matrix molecules called chondroitin sulfates, located in the outside nerve cells ...
The mechanisms underlying the pathogenesis of epilepsy, a neurological disorder characterized by excessive electrical activity in the brain, remain unknown. Now, using a novel radiotracer ([11 C]K-2, ...
Like vertebrates, sea slugs engage in simple forms of learning and memory, and they have provided valuable insights into synaptic plasticity. 1 Researchers cultured a bifurcated sensory neuron with ...
New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...