The accurate transmission of genetic information from a cell to a daughter cell is ensured by the tight regulation of the four stages of the cell cycle. The stages of this cycle include: Gap 1 (G1) ...
DONGTAN, KOREA, October 7, 2024 - iLeadBMS, a spin-off biotech from Ildong Pharmaceutical Group, announced that it has received a notification from the US Food and Drug Administration (FDA) that its ...
Circle Pharma, a leader in macrocycle drug discovery and development, announced the submission of its first Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) ...
Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder affecting roughly 1 in 3,500 males. DMD is due to mutations in the dystrophin gene, which encodes for an exceptionally large 427 kD ...
1 Division of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada 2 Canada’s Michael Smith Genome Sciences Centre, British Columbia (BC) Cancer, Vancouver, ...
Recently, we have reported that the cyclin B2/CDK1 complex regulates homologous chromosome segregation through inhibiting separase activity in oocyte meiosis I, which further elucidates the ...
Survival data following phase 1/2 studies using precision tumor-targeted gene delivery to advanced chemotherapy-resistant malignancies. This is an ASCO Meeting Abstract from the ASCO Breakthrough: A ...
Loss of proteostasis and cellular senescence are key hallmarks of aging, but direct cause-effect relationships are not well understood. We show that most yeast cells arrest in G1 before death with low ...
Characterization of OASEP1 as a biomarker and therapeutic target for oral cancer. Impact on U251 glioma cell radiosensitivity and CFL1 level via inhibiting cell motility regulator ROCKII of ...