Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

This is the live blog for the 49ers' Week 13 road game against the Buffalo Bills. This will be updated frequently with ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

After exiting San Francisco's Sunday Night Football contest at the Buffalo Bills during the first half with a knee injury, ...

Facing a first-and-goal from the 49ers' 9-yard line, already up 21-3 on San Francisco, Allen initially hit Cooper in the flat ...

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Buffalo Bills star quarterback Josh Allen pulled off another mind-blowing touchdown that had the football world buzzing.

San Francisco 49ers star running back Christian McCaffrey receives huge injury update following his exit from the game due to ...

San Francisco star running back Christian McCaffrey exited the 49ers Sunday Night Football game against the Bills with a knee ...

Josh Allen grabbed at his left hand and jumped in pain after he took on 49ers linebacker De'Vondre Campbell Sr.

We're live with the Week 13 edition of "Sunday Night Football" as the Buffalo Bills play host to the San Francisco 49ers to ...