Facing a first-and-goal from the 49ers' 9-yard line, already up 21-3 on San Francisco, Allen initially hit Cooper in the flat ...

Buffalo Bills star quarterback Josh Allen pulled off another mind-blowing touchdown that had the football world buzzing.

After exiting San Francisco's Sunday Night Football contest at the Buffalo Bills during the first half with a knee injury, ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

San Francisco 49ers running back Christian McCaffrey went down with an apparent non-contact knee injury early in the second ...

Buffalo Bills tight end Dawson Knox takes San Francisco 49ers safety Ji'Ayir Brown for a ride on a 39-yard catch and run.

RB Christian McCaffrey, playing in just his fourth game since returning from an Achilles injury, left Sunday night's game at ...

The Buffalo Bills will be without rookie wide receiver Keon Coleman in their Week 13 Sunday Night Football clash with the San Francisco 49ers, Fox Sports insider Jordan Schultz reports. The ...

San Francisco 49ers running back Jordan Mason refuses to be tackled on a 27-yard burst. Buffalo Bills running back James Cook ...

Buffalo Bills quarterback Josh Allen is now the franchise's sole leader in all-time total touchdowns. It’s long been obvious that quarterback Josh Allen would go down as one of, if not the, most ...

Buffalo has run consistently over the previously perceived vaunted 49ers defense to jump up to a halftime lead.