With this expansion came a better understanding of associated complications. Spinal cord ischemia, perhaps the most dreaded complication of aortic surgery short of death, led to an understanding of ...

BACKGROUND: Aortic valve disease (AVD) is associated with high mortality and morbidity. To date, there is no pharmacological ...

There never has been another operation like coronary bypass surgery. There is more evidence, and more good evidence through randomized trials and large observational studies, that coronary bypass ...

Background: Patients with heart failure (HF) with mildly reduced or preserved ejection fraction face heightened long-term risks of morbidity and mortality. The sodium glucose-co-transporter-2 ...

Cardiac ischemia/reperfusion (I/R) injury has emerged as an important therapeutic target for ischemic heart disease. Currently, there is no effective therapy for reducing cardiac I/R injury.

Background: Loss of cardiomyocytes without replenishment is one of the main cellular mechanisms leading to heart failure. Promoting cardiomyocyte proliferation and heart regeneration has become a ...

Cardiac arrhythmias are commonly noted in patients during infections with and recovery from COVID-19. Arrhythmic manifestations span the spectrum of innocuous and benign to life-threatening and deadly ...

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Our concepts about the acute coronary syndromes have evolved markedly since the founding of the American Heart Association a century ago. Mason Sones accidentally discovered the ability to perform ...