gut.bmj

Crosstalk between liver sinusoidal endothelial cells and hepatocytes via IL-1α–IL1R1 axis exacerbates ischaemia/reperfusion injury in aged livers

Background With population ageing, elderly patients account for a growing proportion of hepatic surgery recipients. Hepatic ischaemia-reperfusion injury (HIRI) is a major cause of postoperative liver ...
gut.bmj

Oral budesonide is as effective as oral prednisolone in active Crohn’s disease

Professor M Campieri, Medical and Gastroenterological Clinic, University of Bologna, Policlinico S Orsola, Via Massarenti, 9, I-40138 Bologna, Italy. Background—The use of corticosteroids in active ...
gut.bmj

Real-world validation of a prognostic clinical index to predict steroid response in acute severe colitis: a single tertiary centre retrospective study

We read with great interest the article by Adams et al in *Gut* on the development and validation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) score to ...
gut.bmj

Risk of new or recurrent cancer under immunosuppressive therapy in patients with IBD and previous cancer

4 Registre Bourguignon des Cancers Digestifs F-21079; Inserm U866; CHRU Dijon; Université de Bourgogne, Dijon, France Objective To explore the risk of new or recurrent cancer among patients with IBD ...
gut.bmj

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

2 Departments of Biochemistry and Medical Microbiology and Immunology, Li Ka Shing Insitute of Virology, University of Alberta, Edmonton, Alberta, Canada Objective Hepatitis C virus (HCV) infection ...