Gut

Does a long time to colonoscopy after a positive faecal immunochemical test result have a deleterious impact on colorectal cancer outcomes? A nationwide cohort study

Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months ...
Gut

Potential of GDF15 goes beyond its role as a non-invasive biomarker for MASLD

We read with great interest the article of Ratziu and colleagues, who evaluated the potential of thrombospondin-2 (TSP2), insulin-like growth factor binding protein 7, CD163 and growth differentiation ...
Gut

Intraperitoneal translocation of gut microbiota induces NETosis and promotes endometriosis

Background Endometriosis is a debilitating gynaecological disorder with an elusive pathogenesis. While gut microbiota dysbiosis has been implicated, the causal role of gut-peritoneum microbial ...
Gut

Gut microbe alleviates stress-related cancer metastasis by oleic acid degradation

Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...
Gut

Discovery of a carboxyl fullerene derivative as a new lipid droplet regulator inhibiting MASLD

Background The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing with high ...
Gut

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection

Background Chronic hepatitis B virus (HBV) infection disproportionately affects people living with HIV, who are often excluded from functional cure studies. Objective This study investigates CD8+ T ...
gut.bmj

Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice

Objective Faecal microbiota transplantation (FMT) has proved to be an extremely effective treatment for recurrent Clostridioides difficile infection, and there is interest in its potential application ...
gut.bmj

Prevention of rebleeding after primary haemostasis using haemostatic powder in non-variceal upper gastrointestinal bleeding: a multicentre randomised controlled trial

2 Utah-Inha DDS & Advanced Therapeutics Research Center, Incheon, Korea (the Republic of) Background Non-variceal upper gastrointestinal bleeding (NVUGIB) remains a major cause of morbidity and ...
gut.bmj

miR-301a promotes intestinal mucosal inflammation through induction of IL-17A and TNF-α in IBD

Objective MicroRNA (miR)-301a is known to be involved in the tumourigenesis and pathogenesis of several autoimmune diseases, but it remains unclear whether miR-301a is associated with the pathogenesis ...
gut.bmj

Gastric adenocarcinoma screening and prevention in the era of new biomarker and endoscopic technologies: a cost-effectiveness analysis

Objective To estimate the cost-effectiveness of noncardia gastric adenocarcinoma (NCGA) screening strategies based on new biomarker and endoscopic technologies. Design Using an intestinal-type NCGA ...
gut.bmj

Bacterial infection causes stress-induced memory dysfunction in mice

Background The brain–gut axis is a key regulator of normal intestinal physiology; for example, psychological stress is linked to altered gut barrier function, development of food allergies and changes ...
gut.bmj

Endoscopic mucosal resection for treatment of early gastric cancer

Dr H Kondo, Department of Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.htkondoh{at}ncc.go.jp BACKGROUND In Japan, endoscopic ...