Duke is the tournament’s betting favorite thanks to Flagg, the projected No. 1 overall pick in the upcoming NBA draft, and a couple more first-round prospects. The Blue Devils went 19-1 in ACC play and finished the season with the nation’s largest average margin of victory (20.8 points per game). Jon Scheyer’s group is rolling.

NCAA Tournament is here and it’s time to dish out strategies for filling out your March Madness brackets. Every year we have surprise teams making runs to the Sweet 16, Elite Eight or Final Four. Picking the right upsets could be the difference between winning or losing your NCAA Tournament bracket pools.

FOX Sports' John Fanta breaks down the East Region of the NCAA Tournament, including must-see players, first-round upsets and his pick to come out of the region.