San Francisco running back Christian McCaffrey was officially ruled out of the 49ers’ Sunday Night Football contest at the ...

San Francisco 49ers fans held their collective breath Sunday when Christian McCaffrey went down with a non-contact injury in ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

San Francisco 49ers' standout running back Christian McCaffrey sustained a knee injury during the second quarter against the ...

San Francisco 49ers running back Christian McCaffrey bulldozes a Buffalo Bills defender into to the snowy gridiron during a 20-yard run.

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) tries to avoid Buffalo ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

San Francisco 49ers running back Christian McCaffrey is questionable to return to Sunday night's game against the Buffalo Bills with a knee injury.

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers’ medical tent and ...