The Herons have been reliant on their Argentine No. 10, and he pushed them to the last 16 of the Club World Cup, taking down Porto in the process. With Segovia and Tadeo Allende, there are other players who can step up to assist Luis Suarez in the attack, but Mascherano will need to determine the best setup if their star misses any time.

The Leagues Cup has brought Lionel Messi and Inter Miami happy memories in the past, but this season's edition has proven painful early on.

Lionel Messi left the pitch just 11 minutes into Inter Miami’s match against Necaxa with a suspected hamstring issue. Tests will determine the extent of the injury. Associated Press and Telemundo report that Lionel Messi left Saturday night’s Leagues Cup match between Inter Miami and Necaxa after appearing to suffer a right hamstring injury just minutes into the game.