Traditional drug research has focused on creating inhibitors that occupy the active areas of disease-related proteins, preventing them from functioning properly. But this strategy leaves a ...

In this study, the TransformerCPI was utilized to identify two natural compounds, Polyphyllin V and Polyphyllin H, targeting ...

(MEMPHIS, Tenn. – September 22, 2025) LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation ...

With several antibodies to mop up amyloid plaques coming into routine use, the big challenge for scientists has become to find ways to temper tau pathology. Two different studies report some news on ...