For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon raises it. But that’s much too simple, new research says.

For years, scientists have focused their attention on the pancreas’ insulin-producing beta cells and left small clusters of ...

G protein-coupled receptors (GPCRs) are essential for cell signal transduction and comprise the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple ...

Glucagon-like peptide-2 (GLP-2) is a gut-derived hormone principally secreted by enteroendocrine L cells in response to nutrient ingestion. It plays a pivotal role in maintaining intestinal integrity ...

New findings raise the possibility of promising therapeutic strategies for the management of hypoglycemia in type 1 diabetes patients. Study: Loss of electrical β-cell to δ-cell coupling underlies ...

Glucose metabolism in mammalian species and teleost fish is controlled by different metabolic pathways. These include differences in the function of several major hormones, especially insulin and ...

New insights into the underlying mechanisms of Type 2 diabetes and novel potential therapeutic targets for the disease were revealed in a recent study by a team of Texas A&M AgriLife Research ...

Researchers at the University of Alabama at Birmingham, and Southern Research, have identified a new drug candidate that they claim could represent a “distinct and innovative” approach to treating ...

Wanbao Yang, Ph.D., (left) graduate student and the study’s first author, and Shaodong Guo, Ph.D., who served as its principal investigator. (Texas A&M AgriLife photo by Tyler Morales) The study, ...