The Buffalo Bills updated fans on their progress of removing snow at Highmark Stadium ahead of their matchup with the San ...

The Buffalo Bills (9-2) will try to build on a six-game winning streak when they host the San Francisco 49ers (5-6) on Sunday ...

San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's ...

The Buffalo Bills have the opportunity to accomplish something no NFL team has achieved since 2009 in Week 13.

Christian McCaffrey is projected as the most likely anytime touchdown scorer for Sunday Night Football as the San Francisco ...

The San Francisco 49ers are reeling. They've lost two straight games to fall to 5-6 and under .500 for the fourth time this ...

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local ...

We've seen this before in Buffalo -- a lake effect snowstorm dumps tons of snow on Highmark Stadium for a Bills game. That's ...

The Bills return from the bye for a primetime showdown with the 49ers in NFL Week 13 on Sunday, Dec. 1 at Highmark Stadium.

Running back Christian McCaffrey says the San Francisco 49ers are “hungry” to make a playoff push even with the defending NFC ...

The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...