High-intensity focused ultrasound (HIFU) is an increasingly used, locally ablative therapy option in localized prostate cancer (PCa). Multiparametric MRI (mpMRI) is currently used for tumor ...

Nuclear medicine has undergone a remarkable transformation, with both diagnostic and therapeutic applications expanding at an unprecedented pace. This progress is rooted in fundamental discoveries by ...

Radiotheranostics refers to dual diagnostic–therapeutic capacity that allows for precision medicine at an unprecedented level, reducing collateral toxicity and improving patient outcomes ([1][1]). In ...

PET scans are used in the diagnosis and staging of various cancers, with [18 F]FDG the most widely used radiotracer (1). The glucose analog FDG utilizes the increased glucose demand of many tumors ...

Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been ...

Journal of Nuclear Medicine November 2025, jnumed.125.270481; DOI: https://doi.org/10.2967/jnumed.125.270481 ...

Journal of Nuclear Medicine November 2025, jnumed.125.270710; DOI: https://doi.org/10.2967/jnumed.125.270710 ...

Quantitative 18F-FDG PET is increasingly being recognized as an important tool for diagnosis, determination of prognosis, and response monitoring in oncology. However, PET quantification with, for ...

Lewy body diseases (LBDs) feature profound myocardial depletion of the sympathetic neurotransmitter norepinephrine. In addition to sympathetic neuronal loss, the norepinephrine deficiency may reflect ...

18 F-FDG PET Reveals Voxel-Based Decreases in Brain Glucose Uptake After Chemotherapy in Leukemia Patients: A Retrospective Matched-Control Study ...

For staging of cancer patients, 18F-FDG PET imaging has been applied for about a decade. It is generally accepted that imaging the metabolic activity of tumor tissue provides more sensitive and more ...

SPECT is a powerful tool for noninvasive imaging of molecular processes in living organisms (1). A strength of SPECT is its capability to image multiple radioisotopes simultaneously based on spectral ...