Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...

Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we ...

Flare Therapeutics Inc. (FlareTx), a clinical-stage biotechnology company targeting transcription factors to discover precision medicines for oncology and other therapeutic areas, today announced that ...

Gastrointestinal stromal tumors (GISTs) are the most common type of sarcoma, often driven by mutations in the KIT or PDGFRA ...

Jie Dong, Ning Sun, Jing Yang, Zhaoguo Deng, Jingqiu Lan, Genji Qin, Hang He, Xing Wang Deng, Vivian F. Irish, Haodong Chen, Ning Wei, The Transcription Factors TCP4 and PIF3 Antagonistically Regulate ...

Computational research in fruit flies revealed how spontaneously arising genes are tightly controlled, offering insights into ...

Median Overall Survival (OS) of 15 months for subjects with complete remission (n=8)Median OS of 2nd Line efficacy evaluable population of 12 ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report ...

A team of researchers led by Professor Yoko Hamazaki and Assistant Professor Yann Pretemer (Department of Life Science ...

H umans are the only primates that walk on two legs. Scientists believe that their uniquely shaped pelvis, the bones that ...