The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better ...

To disarm toxic substances, many organisms - including humans - possess enzymes called flavin-containing monooxygenases. Despite their importance, the structure of the enzymes has not been ...

A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19.

A research team has discovered the structure of a novel RNA-modifying enzyme, ZCCHC4, and identified the mechanism that controls how this enzyme recognizes its substrate. ZCCHC4 influences cell ...

Researchers from the University of Chicago and Argonne National Laboratory have deciphered the three-dimensional structure of insulin-degrading enzyme, a promising target for new drugs because it ...

A report of the study, published online Monday (April 7) in Nature Structural Biology, presents the first crystal structure of the protein human carboxylesterase 1, or hCE1.

The mystery, which has evaded scientists for more than five decades, can be explained with rather simple chemistry, according to a study published Wednesday in Nature. In lab experiments, scientists ...

The University of California, Riverside, discovery can be used for structure-based drug design against cancers and lead to a better understanding of how m6A, a modification associated with ...

A Cornell-led collaboration has devised a potentially low-cost method for producing antibodies for therapeutic treatments.