Accurate quantitative analysis revealed that most purine nucleotides occur in calf-thymus DNA in sequences of two or more purine nucleotides3.

The scientists show how purines and pyrimidines can form from a common precursor molecule that could have existed before life on Earth began. They find 8-oxo-purine shares underlying similarities ...

Activated 8-oxo-purine nucleotides were incorporated into a growing RNA strand at a much slower rate than the canonical nucleotides.

The team demonstrated how purines and pyrimidine nucleotides can both be assembled on the same sugar scaffold to form molecules called ribonucleotides which are used to construct RNA.

Purine Metabolism: The series of biochemical processes involved in the synthesis, recycling, and degradation of purine nucleotides.

The study's results focused on biological pathways related to the breakdown of chemical compounds known as purine nucleotides.

Plants can fully catabolize purine nucleotides. A firmly established central intermediate is the purine base xanthine. In the current widely accepted model of plant purine nucleotide catabolism, ...

Both salt treatments reduced root growth by more than 30%. The capacity of roots to provide purine nucleotides either by de novo synthesis or by re-utilization of existing bases, e.g. salvage of ...

Active MTHFD2-mediated one-carbon metabolism consumes AICAR and produces IMP and purine nucleotides for cancer cell proliferation. Reduced intracellular pool of AICAR is essential for maintenance ...

Here we perform a systematic biochemical screen for bacterial signalling nucleotides and discover a large family of cGAS/DncV-like nucleotidyltransferases (CD-NTases) that use both purine and ...

The synthesized purines have one extra oxygen atom relative to natural nucleotides, but they maintain an arrangement of atoms that allows Watson-Crick base pairing. Purines with an extra oxygen atom ...

Applications of Sustainable Chemistry in the Synthesis of Nucleosides, Nucleotides and Oligonucleotides Organic Chemistry Division ...