Speaking at HIV Management 2007: The New York Course, Daniel Douek, MD, MRCP, PhD, offered an alternative hypothesis to the long-accepted model of gradual CD4+ T-cell depletion. Dr. Douek discussed ...

Can Antiretroviral Therapy Be Stopped? The success of our current therapies, along with the identification of long-lived reservoirs of infectious virus, raises a question about whether therapy can ...

HIV infection is associated with numerous adverse renal manifestations, including HIV-associated nephropathy (HIVAN), HIV-associated immune complex kidney disease (HIVICD), and other ...

Monkeys infected with simian immunodeficiency virus have a higher diversity of gut viruses, pointing to a possible role of the virome in SIV pathogenesis. A series of rodent experiments showed that ...

The author(s) indicated no potential conflicts of interest. Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Aviano, Italy; WHO International Agency for Research on ...

This article, the first in a three-part series, gives a brief history and current picture of HIV prevalence, and describes its pathophysiology and modes of transmission. Part 2 will explain the signs ...

Background. Although the determinants of immune deficiency and immune restoration in chronic human immunodeficiency virus (HIV)-1 infection are not well understood, immune activation has been proposed ...

A protein related to heart disease and Alzheimer's is found to be a factor in HIV. The apolipoprotein (apo) E4 isoform has been implicated in neurodegeneration in Alzheimer's disease, cardiovascular ...

Patients with HIV infection are at increased risk for both acute kidney injury and chronic kidney disease. 4,9,10,12,16–18 Untreated HIV infection, as well as antiretroviral therapy, are associated ...

The author(s) indicated no potential conflicts of interest. Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Aviano, Italy; WHO International Agency for Research on ...