Combining tissue profiling with whole transcriptome spatial analysis and high-plex protein co-detection enables a deeper, more holistic understanding of tissue organization "The continued expansion of ...
The pancreas is a dual-purpose organ with exocrine (digestion) and endocrine functions (hormone secretion for blood glucose regulation) 1. Endocrine cell types and functions are localized to ...
Tuberous sclerosis complex (TSC) is an autosomal-dominant disorder caused by loss-of-function mutations in the tumor suppressor genes TSC1 and TSC2, leading to constitutive hyperactivation of the ...
The study utilized spatial transcriptomics (10X Visium) to map gene expression from embryonic day 12.5 (E12.5) to postnatal day 0 (P0). This graphical abstract illustrates the comprehensive ...
A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...
Top: Hematoxylin and eosin (HE) staining of the epipharyngeal mucosa. Bottom: Clustered gene expression map obtained from the same tissue section using Visium HD spatial transcriptomics. Credit must ...
A series of announcements in recent weeks shows just how much the spatial biology field has matured in the years since Nature Methods recognized spatial biology—which it called spatially resolved ...
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