Programed cell death 4 (Pdcd4) is a novel tumor suppressor that frequently exhibits downregulated expression in several types of cancer. In colon cancer tissues, expression level of Pdcd4 is ...
Loss of functional adenomatous polyposis coli (APC) protein results in the stabilization of cytosolic β-catenin and activation of genes that are responsive to Lef/Tcf family transcription factors. We ...