T cell development in the thymus is a highly coordinated process involving differentiation, migration, and selection to establish a self-tolerant and functional immune repertoire. Bone marrow-derived ...
The thymus is crucial for T cell development, and its lobules consist of cortical (C) and medullary (M) regions that facilitate the movement of developing T lymphocytes 1,2,3. Typically, CD3 + CD4-CD8 ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
Chimeric antigen receptor (CAR) T-cell therapies have transformed cancer and autoimmune disease treatment. Modified CAR proteins equip T cells with the ability to identify and eliminate cancer cells ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results