In a randomized clinical trial with 4,446 participants, known as the Anal Cancer/HSIL Outcomes Research (ANCHOR) study, researchers found that by removing high-grade squamous intraepithelial lesions ...

Please provide your email address to receive an email when new articles are posted on . Treating high-grade squamous intraepithelial lesions — primarily with office-based electrocautery — led to an ...

Medically reviewed by Andrea L. Braden, MD Key Takeaways Have regular Pap smears that check for abnormal squamous cells, which may be harmless or may be signs of HPV.Discuss abnormal Pap smear test ...

Incidental finding of pulmonary nodule on CT pulmonary angiogram (CTPA) in view of current surveillance recommendations: Is any lung cancer screening protocol applicable? Evaluation of machine ...

The new trial was the first to investigate outcomes among a patient population living with HIV (PLWH) who were treated for anal precancerous growths, or high-grade squamous intraepithelial lesions.

Using an index designed and validated for use in ANCHOR, HRQoL was assessed before random assignment (T1), 2-7 days (+3 days) after random assignment/treatment (T2), and 28 days (±7 days) after random ...

Treating precancerous anal lesions in people with HIV reduced their risk of developing anal cancer by more than half compared with active monitoring, according to results from the ANCHOR study. In the ...

Inovio Pharmaceuticals Inc. has “more work to do” in understanding mixed results with the DNA-based immunotherapy VGX-3100 as a treatment for cervical high-grade squamous intraepithelial lesions ...

Like cervical cancer, anal cancer is often caused by a human papillomavirus and has a premalignant stage called high-grade squamous intraepithelial lesion or anal intraepithelial neoplasia. A ...

The distribution of human papillomaviruses (HPVs) must be understood for the control and prevention of cervical cancer. Community-based Papanicolaou and HPV DNA tests were performed on 41 578 women.