Recombineering (recombination-mediated genetic engineering) is a genetic and molecular biology technique based on homologous recombination systems, as opposed to the older/more common method of using ...

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations. CRISPR-Cas9 can be programmed to find and cut specific pieces ...

Researchers in the Blavatnik Institute at Harvard Medical School (HMS) and the Biological Research Center in Szeged, Hungary, say they have developed a new genetic engineering technique that promises ...

Could a new technique – Retron Library Recombineering – consign CRISPR to the history books? No regular BioTechniques reader will be unfamiliar with both the promise and challenges posed by CRISPR.

COLD SPRING HARBOR, N.Y. (Tues., Sept. 1, 2009) – Chromatin Immunoprecipitation (ChIP) is an invaluable method for studying the interactions between proteins and DNA on a genome-wide scale. ChIP can ...

Retron-based genome editing has been inviting comparisons with CRISPR-based genome editing, especially since researchers have learned that retrons, like CRISPR systems, function as a sort of immune ...

There is a new gene-editing tool called Retron Library Recombineering (RLR) that makes this task easier that has been developed by George Church and his team. RLR generates up to millions of mutations ...

Researchers have created a new gene editing tool called Retron Library Recombineering (RLR) that can generate up to millions of mutations simultaneously, and 'barcodes' mutant bacterial cells so that ...