Irisin, a hormone released during exercise, appears to directly shield neurons from damage in a mouse model of multiple ...

The use of iPSC-derived neurons to model human diseases like Alzheimer’s has enabled new advances. Nonetheless, a limitation of these cells is that their reprogramming resets epigenetic marks, erasing ...

Researchers have used microRNA-based direct reprogramming to generate neurons from fibroblasts, providing new insights into late-onset Alzheimer’s disease. Aging is the most significant risk factor ...

The findings, published in Nature on July 19, shed light on potential neural mechanisms involved in working memory and decision making. "Our study is a step toward thinking of the brain not in terms ...

The spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer’s disease and frontotemporal dementia—has been studied with a model that incorporates human ...

An EEG (electroencephalogram) is a painless test that uses small sensors placed on the scalp to measure the brain’s electrical activity. It provides a real-time readout of brain “waves”—rhythms ...

The brain alone contains billions of neurons, specialized cells that send and receive electrical signals throughout the body. Performing a task such as writing a story uses only about 20 watts of ...

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...