Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also discovered the ...

The sarcomere is the most basic contractile unit in skeletal and cardiac muscle. Mutations in genes encoding sarcomeric proteins give rise to heritable myopathies, although muscle function is more ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Researchers at UT Southwestern Medical Center at Dallas are the first to use genetically engineered mice containing a fluorescent molecule to examine in real time the chemical reactions that result in ...

The three-dimensional folding of DNA provides important epigenetic mechanisms in the formation of cardiac muscle cells. During differentiation of pluripotent stem cells to cardiomyocytes, the ...

Cardiac muscle tissue is only found in your heart. It performs involuntary, coordinated contractions that allow your heart to pump blood through your circulatory system. Cardiac muscle tissue is one ...

The paper by Parmley et al. in this issue calls attention to the possible therapeutic use of glucagon in view of its possible inotropic and chronotropic effects in man. Such effects have previously ...

Type IIb fast-twitch myofibers, known for their rapid contraction speed, are plentiful in small mammals but have largely diminished in humans. Researchers at the University of Tsukuba have discovered ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...