The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium ...

Researchers at UT Southwestern Medical Center at Dallas are the first to use genetically engineered mice containing a fluorescent molecule to examine in real time the chemical reactions that result in ...

The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...

IT is generally believed that the process which initiates contraction in striated muscle is the depolarization of the excitable membrane of the muscle fibre, although the mechanism by which membrane ...

This is a preview. Log in through your library . Journal Information PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, ...

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study. The flow of water within a muscle fiber may dictate how quickly muscle can contract, ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Type IIb fast-twitch myofibers, known for their rapid contraction speed, are plentiful in small mammals but have largely diminished in humans. Researchers at the University of Tsukuba have discovered ...

Muscle is known to regenerate through a complex process that involves several steps and relies on stem cells. Now, a new study led by researchers at Pompeu Fabra University (UPF, Spain)/Centro ...

Skeletal muscle is the most abundant tissue of the human body (about 40%) and it plays essential role in locomotion and vital functions (heart rate, breathing). During aging, in a large majority of ...