For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon ...

G protein-coupled receptors (GPCRs) are essential for cell signal transduction and comprise the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple ...

Glucose metabolism in mammalian species and teleost fish is controlled by different metabolic pathways. These include differences in the function of several major hormones, especially insulin and ...

Glucagon-like peptide-2 (GLP-2) is a gut-derived hormone principally secreted by enteroendocrine L cells in response to nutrient ingestion. It plays a pivotal role in maintaining intestinal integrity ...

For years, scientists have focused their attention on the pancreas’ insulin-producing beta cells and left small clusters of ...

New findings raise the possibility of promising therapeutic strategies for the management of hypoglycemia in type 1 diabetes patients. Study: Loss of electrical β-cell to δ-cell coupling underlies ...

New insights into the underlying mechanisms of Type 2 diabetes and novel potential therapeutic targets for the disease were revealed in a recent study by a team of Texas A&M AgriLife Research ...

BIRMINGHAM, Ala. - The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes. Tested on isolated ...

Wanbao Yang, Ph.D., (left) graduate student and the study’s first author, and Shaodong Guo, Ph.D., who served as its principal investigator. (Texas A&M AgriLife photo by Tyler Morales) The study, ...