INTRODUCTION. Genotoxicity refers to the property of hazardous (physical, chemical and biological) agents to cause damage to genetic information present within a cell. It is worth mentioning that this ...

Driven by the stringent regulatory guidelines issued to ensure safety of end-user and the growing pipeline of healthcare products, the demand for genotoxicity / mutagenicity testing has grown ...

The US Food and Drug Administration (FDA) announced it has released new, harmonized guidance for sponsors looking to conduct genotoxicity testing and data interpretation for human drug products. The ...

Enveric Biosciences (ENVB) said Tuesday it started genotoxicity studies for its primary drug candidate, EB-003, to prepare for an investigational new drug filing. The laboratory assessments will ...

An international research team has developed an in vitro transcriptomic biomarker that can predict, with up to 90% accuracy, whether a drug candidate or other chemical compound is likely to cause the ...

A new biomarker test can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer. A new biomarker test developed by researchers at ...

The International Conference on Harmonization (ICH) steering committee and working groups met in Seville, Spain, earlier this month. The groups meet twice annually to discuss, revise, and approve ...

In conjunction with the University of Manchester, Gentronix has been granted a research award of £133,024 by the National Centre for the Replacement, Refinement and Reduction of Animals in Research ...

CYPROTEX, the Macclesfield-based drug testing company, said that it has added a new service line providing automated, high content screening service to detect genotoxicity. The firm said the service ...

The toxicological testing market is no stranger to the principle of the three Rs of research: replacement, reduction, and refinement. With that to guide us, we will review ways to fulfill these ...

Intramuscular implantation assesses local tissue response to an implanted material for the ISO 10996-6 implantation test. However, manufacturers are on their own when it comes to how best to fulfill ...