DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

The secretory pathway comprising the ER, Golgi apparatus and plasma membrane is central in the growth and development of the eukaryotic cell. Membrane-bound and soluble molecules that are destined for ...

A collaborative French–Swiss study reveals a previously unknown role for astrocytes in the brain's information processing.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 1 (January 4, 2022), pp. 1-7 (7 pages) Recent advances in super-resolution microscopy revealed the ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

Paul Victor, Dhamodharan Umapathy, Leema George, Udyama Juttada, Goutham V. Ganesh, Karan Naresh Amin, Vijay Viswanathan and Kunka Mohanram Ramkumar Increasing evidence in substantiating the roles of ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

HGS-ETR1, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: Results of a phase 1 and PK study Ca++ mobilization leading to ...

A collaborative French-Swiss study reveals a previously unknown role for astrocytes in the brain's information processing. Dozens of synapses ...