The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

Find out how to watch the NFL Week 16 game between the San Francisco 49ers and Indianapolis Colts, as well as the latest odds.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

Brock Purdy stats: 49ers QB makes MNF history with career game vs. Colts originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here.

The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and the win keeps them alive for an NFC West title and a shot at the No. 1 seed ...

By winning Monday night’s final regular-season road game in a 48-27 shootout over the Colts, the 49ers remained in control of ...

Monday Night Football schedule, TV channel, time, streaming information for San Francisco 49ers vs Indianapolis Colts NFL ...

San Francisco 49ers running back Jordan James looks ready to take a bigger role in 2026 after showing promise in limited ...

The San Francisco 49ers will be in action Monday night against the Indianapolis Colts. They've moved three players to the roster for the game.