Calcific aortic stenosis has many characteristics in common with atherosclerosis, including hypercholesterolemia. We hypothesized that intensive lipid-lowering therapy would halt the progression of ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

New insights into the prevalence of aortic valve calcification—and its progression—among carriers of a common genetic mutation may reopen a long-simmering debate about the role of statins in ...

(UPDATED) Lipoprotein(a) is associated with the development of aortic valve calcification (AVC), but the atherogenic lipoprotein does not appear to be linked to the progression of calcification over ...

In the paper, Cowell and colleagues explain that calcific aortic stenosis is an inflammatory-disease process that has many similarities with atherosclerosis. Several studies have revealed a clinical ...

OAK BROOK, Ill. - Computed tomography (CT)-based measures of calcification in the abdominal aorta are strong predictors of heart attacks and other adverse cardiovascular events--stronger even than the ...

In asymptomatic patients with mild to moderate aortic stenosis, the survival is similar to age-matched controls. [1,16] The mainstay of medical treatment for these patients is simply appropriate ...

Researchers have analyzed gene expression and protein distribution in human aortic valves obtained from valve replacement surgery. Calcific aortic valve disease (CAVD) -- a disease that leaves the ...

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification. They also theorize that other risk factors for CAVD, such as high ...

Calcific aortic valve disease (CAVD) - a disease that leaves the aortic valve stiff and calcified, preventing blood flow from the heart into the aorta - affects one quarter of the U.S. population aged ...