The primary rationale for middle-down proteomics is the need for high-confidence proteoform analysis that is also scalable. A proteoform is defined by its full complement of modifications and sequence ...

Multidimensional chromatography has emerged as a viable alternative to gel-based separation protocols in high-throughput bottom-up proteomics in recent years. Although originally dominated by the ...

Since its inception, bottom-up proteomics has aimed to identify and quantify the complete proteome from a cell, tissue, or whole organism. Although many advances have been made in the last 15 years, ...

The new Thermo Scientific µPAC Neo HPLC Column brings improved column-to-column reproducibility and better protein identification to proteomics researchers MINNEAPOLIS--(BUSINESS WIRE)--ASMS 2022 – ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...