Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

New research reveals that a fundamental process in bacterial gene regulation called sigma cycle, long thought to involve the release of a key protein, sigma factor, might not be universal, opening new ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-9 (9 pages) Horizontal gene transfer drives bacterial evolution. To confer ...

A new report from the Centers for Disease Control and Prevention on the deadly drug-resistant bacteria NDM-CRE found a 70% ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

A recent study has unveiled how plants and bacteria exchange genes to boost plant health and development. The team discovered 75 genes that were transferred between small, fast-growing plants ...

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

Everyday substances, including caffeine, can trigger changes in bacteria like E. coli that make antibiotics less effective. Caffeine activates a regulatory path involving a bacterial protein called ...