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Mutations were identified by screening reaction products with a universal DNA microarray4, which uncouples mutation detection from array hybridization and provides for high sensitivity.
Tumor heterogeneity is another factor that may complicate the interpretation of array CGH data. Furthermore, array CGH may not fully appreciate tumor heterogeneity as DNA copy number changes in a ...
The research group used this high-throughput genomic array to develop an atlas of DNA methylation profiles across more than 1200 samples that included a range of cell types, strains and pathologies.
DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...
Article Title Nanoscale-tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo ...
A new method for reading DNA (or RNA) microarrays is based on measuring the electrostatic repulsion between silica microspheres and hybridized DNA. Surface areas containing double-stranded DNA ...
New Arrays Open 'Junk DNA' to Exploration Microarrays present researchers with something of a catch-22: In order to find something, you have to know what you're looking for.
Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision. Science Advances, 2023; 9 (32) DOI: 10.1126/sciadv.adh8508 ...
Invention could improve DNA-based computing. New York University scientists report the first time that a functional nanotechnology device within a DNA array has been developed. Nadrian C. Seeman ...
image: Single-strand DNA can be anchored to a gold substrate for use in biodetectors by attaching a tail of adenine bases. Adenine's strong affinity for gold not only bonds the strands in place ...