New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

A University of Alberta research team has identified a DNA structure that activates the immune system in cancer cells that are usually resistant to immunotherapy, offering hope of new, more effective ...

KDM5 inhibition/disruption selectively induces R-loop-mediated DNA damage and innate immune activation in breast cancer cells, while sparing normal cells, unveiling a tumor-specific therapeutic ...

Perhaps best known as a immune-system boost or antidote to scurvy, vitamin C has been found to rejuvenate aging skin by reactivating genes responsible for cell growth. By promoting DNA demethylation, ...

Most of our genome is often written off as “junk DNA”, meaning it doesn’t encode for genes that get made into proteins. This so-called junk consists of accumulated DNA elements like viral DNA that got ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...

Our ancient past isn't always buried history. When it comes to our DNA, nearly 9% of the human genome is made up of leftover ...

Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides ...