College Football Week 10 Picks
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Washington State will smother Oregon State on Saturday afternoon in the first of two November matchups between the Pac-12 holdovers. The Beavers are marginally better than they looked under coach Trent Bray, who was fired after an 0-7 start. But they aren’t nearly good enough to handle WSU. Or the point spread.
Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks, and it enters Week 10 on a profitable 47-33 combined run on money-line and over/under college football picks since the beginning of 2024.
No. 18 Oklahoma (6-2, 2-2) at No. 14 Tennessee (6-2, 3-2), Saturday, 7:30 p.m. ET (ABC)
This weekend has entertainment value and chaos potential on its horizon. Both befit the unhinged trip that is 2025 FBS play.
Week 10 of the 2025 season is a pivotal point on the college football calendar. Not only does it mark the time at which almost every school in the nation will have played eight games -- or two-thirds of their schedule -- it also heralds the arrival of the first College Football Playoff rankings reveal.
ESPN's Mike Reiss noted Monday morning that flex decisions must be made 12 days before the affected game. That means a decision for the Nov. 9 New England-Tampa Bay game must be made by Oct. 28. As of right now, the Pittsburgh Steelers and Los Angeles Chargers are scheduled for the Week 10 "SNF" slot.
Which NFL teams have the best chances of winning their games on the NFL Week 9 schedule? ESPN Analytics has revealed its Matchup Predictor numbers for the 14 games in the league this week, and they offer some interesting win probabilities.
Week 10 is crucial to the 2025 college football season. It is the final full slate before the first set of College Football Playoff rankings our unveiled, giving us some insight into the selection committee's thought process and how it views the current hierarchy of programs in contention.