The No. 13-ranked Sooners host No. 8 Ole Miss (11 a.m., ABC), marking the start of a stretch of five straight games against teams currently ranked in the AP top 20. Lane Kiffin’s Rebels are looking to rebound after dropping last week’s contest to No. 5 Georgia, while OU is looking to build off an impressive 26-7 win at South Carolina.

The University of Oklahoma Sooners are set to take on Ole Miss Saturday at 11 a.m., but storms could impact the game.

The Oklahoma Sooners take on the Ole Miss Rebels in a Top 15 matchup with College Football Playoff implications.

Here are three bold predictions for 13th-ranked Oklahoma's matchup vs. No. 8 Ole Miss including the Sooners doing something they haven't done since 2010.

Oklahoma is hosting Ole Miss for the first time ever on Saturday, as the No. 13 Sooners welcome the No. 8 Rebels to Memorial Stadium for a critical battle between one-loss SEC teams. After taking a 43-35 loss at Georgia last week, this marks the end of a brutally tough two-game road swing for Ole Miss.

Quarterback Trinidad Chambliss, a Division II transfer who began the season as the Ole Miss backup, was thrust into a starting role after starter Austin Simmons suffered an injury in Week 2. He's completed 62.7% of his passes and thrown for 1,549 yards, eight touchdowns and an interception.

Oklahoma’s coaching staff and quarterback John Mateer challenged the offensive line to step up their game after the Sooners ran for just 48 yards in their loss to Texas.

This article was originally published on www.si.com/college/oklahoma as Oklahoma has Opportunity Against an Ole Miss Defense That's Struggled This Season.

OU football players Jovantae Barnes, Logan Howland, Derek Simmons and Gentry Williams were all listed as questionable for Saturday's game vs. Ole Miss.